শনিবার, ২২ জুন, ২০১৩

'The Voice' Champ Danielle Bradbery Still Isn't Sure She's Actually Famous

'I'm still debating if I'm actually a celebrity,' the 'Voice' champion tells MTV News of her newfound fame.
By James Montgomery, with additional reporting by Natasha Chandel

Source: http://www.mtv.com/news/articles/1709442/the-voice-danielle-bradbery-winner-celebrity.jhtml

kansas city chiefs Javon Belcher express kindle fire Jenny Johnson olivier martinez ny lottery

The Weirdest Thing on the Internet Tonight: Toe Jam (NSFW)

If we're going to keep up the hypocritical charade of, on one hand, expecting pruitanical censorship of human anatomy while, on the other, selling 8-year-olds Juicy Couture then we might as well put those silly black bars to good use. Just look at what the Brighton Port Authority (BPA the band, not BPA the BPA) were able to accomplish. Frickin' PONG.

Toe Jam was the first single off the band's 2008 album, I Think We're Gonna Need a Bigger Boat and features the talents of both David Byrne and Dizzee Rascal.

Source: http://gizmodo.com/the-weirdest-thing-on-the-internet-tonight-toe-jam-ns-534691199

lamichael james acl earthquake los angeles unemployment 2012 nfl draft grades young justice d rose

Compound enhances SSRI antidepressant's effects in mice

June 21, 2013 ? A synthetic compound is able to turn off "secondary" vacuum cleaners in the brain that take up serotonin, resulting in the "happy" chemical being more plentiful, scientists from the School of Medicine at The University of Texas Health Science Center San Antonio have discovered. Their study, released June 18 by The Journal of Neuroscience, points to novel targets to treat depression.

Serotonin, a neurotransmitter that carries chemical signals, is associated with feelings of wellness. Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressants that block a specific "vacuum cleaner" for serotonin (the serotonin transporter, or SERT) from taking up serotonin, resulting in more supply of the neurotransmitter in circulation in the extracellular fluid of the brain.

Delicate balance

"Serotonin is released by neurons in the brain," said Lyn Daws, Ph.D., professor of physiology and pharmacology in the School of Medicine. "Too much or too little may be a bad thing. It is thought that having too little serotonin is linked to depression. That's why we think Prozac-type drugs (SSRIs) work, by stopping the serotonin transporter from taking up serotonin from extracellular fluid in the brain."

A problem with SSRIs is that many depressed patients experience modest or no therapeutic benefit. It turns out that, while SSRIs block the activity of the serotonin transporter, they don't block other "vacuum cleaners." "Until now we did not appreciate the presence of backup cleaners for serotonin," Dr. Daws said. "We were not the first to show their presence in the brain, but we were among the first show that they were limiting the ability of the SSRIs to increase serotonin signaling in the brain. The study described in this new paper is the first demonstration of enhancing the antidepressant-like effect of an SSRI by concurrently blocking these backup vacuum cleaners."

Serotonin ceiling

Even if SERT activity is blocked, the backup vacuum cleaners (called organic cation transporters) keep a ceiling on how high the serotonin levels can rise, which likely limits the optimal therapeutic benefit to the patient, Dr. Daws said.

"Right now, the compound we have, decynium-22, is not an agent that we want to give to people in clinical trials," she said. "We are not there yet. Where we are is being able to use this compound to identify new targets in the brain for antidepressant activity and to turn to medicinal chemists to design molecules to block these secondary vacuum cleaners."

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/HE9cAQ04s_w/130621095717.htm

brandon jacobs brian dawkins emma roberts north korea news north korea news giuliana and bill giuliana and bill

Moldova urges int'l help to resolve border row

CHISINAU, Moldova (AP) ? Moldova's Parliament has called on international partners negotiating a settlement with a breakaway republic to stop separatists from seizing territory in eastern Moldova.

Lawmakers adopted a statement late Friday urging the U.S., the European Union, Russia, Ukraine and the Organization for Security and Cooperation in Europe to "resolve the situation in Trans-Dniester through political and peaceful means, respecting democratic...principles."

Last week separatist leader Yevgeny Shevchuk leader signed legislation that would expand the region to include eight Moldovan villages, saying he would do everything possible to make sure the legislation came into effect.

Moldovan Defense Minister Vitalie Marinuta said the army would respond to any attack on its territory if necessary, adding he did not think the situation would escalate into an armed conflict. Trans-Dniester is not recognized internationally but is supported by Russia.

Russia opposes Moldova signing an association agreement with the EU in November, and Moldovan analysts say Moscow is seeking to destabilize the situation in one of Europe's poorest countries.

Trans-Dniester broke away from Moldova in 1990 fearing it planned to reunite with neighboring Romania and a war broke out in 1992, leaving 1,500 dead. In 2005, the EU and the U.S. joined Ukraine and Russia as negotiators finding a solution for the situation, known as one of the frozen conflicts of the former Soviet Union.

Trans-Dniester, wedged between Moldova and Ukraine, is a narrow strip of land separated by from the rest of Moldova by the River Dniester. Moldova was part of Romania until 1940 when it was annexed to the Soviet Union, but Trans-Dniester was never part of Romania.

Source: http://news.yahoo.com/moldova-urges-intl-help-resolve-border-row-100925620.html

kevin costner whitney houston whitney houston funeral live pat buchanan slither slither naacp glen campbell

Go big or go home: NASA's 1.3 billion-pixel panorama from Mars

NASA researchers have composed an interactive, panoramic view of Mars created with more than 900 exposures taken from the Curiosity rover.

By Elizabeth Barber,?Contributor / June 20, 2013

A slice of the panorama from NASA's Mars rover Curiosity with 1.3 billion pixels in the full-resolution version. It shows Curiosity at the "Rocknest" site where the rover scooped up samples of windblown dust and sand.

NASA/JPL-Caltech/MSSS

Enlarge

This is Mars like we?ve never seen it before.

Skip to next paragraph

' + google_ads[0].line2 + '
' + google_ads[0].line3 + '

'; } else if (google_ads.length > 1) { ad_unit += ''; } } document.getElementById("ad_unit").innerHTML += ad_unit; google_adnum += google_ads.length; return; } var google_adnum = 0; google_ad_client = "pub-6743622525202572"; google_ad_output = 'js'; google_max_num_ads = '1'; google_feedback = "on"; google_ad_type = "text"; // google_adtest = "on"; google_image_size = '230x105'; google_skip = '0'; // -->

NASA has released an interactive, billion-pixel view from the surface of Mars, an amalgamation of some 900 exposures shot from Curiosity?s cameras.

The grand, unearthly view stretches like a timeline of Curiosity?s journey, from the site where Curiosity collected its first rock sample to Mount Sharp, to which the rover is now chugging. The result is a landscape portrait as majestic as any Ray Bradbury novel: a red-brown, rocky desert, sloping to a distant mountain bathed in dust.

"It gives a sense of place and really shows off the cameras' capabilities," said Bob Deen of the Multi-Mission Image Processing Laboratory at NASA's Jet Propulsion Laboratory, in a statement. "You can see the context and also zoom in to see very fine details."

Deen assembled the panorama using some 850 frames from Curiosity?s telephoto camera, along with about 21 frames from its wider-angle camera and some 25 black-and-white frames from the rover?s Navigation Camera. The images were shot on different days in the fall of 2012, showing variation in atmospheric quality and light.

The 1.3-billion-pixel image can be seen at NASA?s website with zoom and pan tools that let earthling explorers tour the red planet. A scaled-down version of the photograph is also available for download.

The raw, single-frames that Curiosity sends home are regularly posted on NASA?s homepage for its rover.

Curiosity has been on Mars since August and has continuously sent back to Earth information that has changed our understanding of the far-off planet. Earlier this June, Curiosity found a rock containing clay-mineral elements that could only have formed in water ? evidence that the dusty planet once had fresh water.

Source: http://rss.csmonitor.com/~r/feeds/science/~3/ITDigjB2FBQ/Go-big-or-go-home-NASA-s-1.3-billion-pixel-panorama-from-Mars

sparkle sacagawea ray allen kobe bryant miami heat first day of summer

Supermoon: Humanity's Fascination Explained

The supermoon may loom large and bright in the sky this Sunday, but the rocky orb will not trigger any natural disasters or even wreak havoc on the tides.

What the full moon's closest approach to Earth will do, however, is continue to fascinate and mystify humanity as it has for millennia.

"When I go outside and look at the full moon I feel very connected to the universe," said Michelle Thaller, the assistant director of science at NASA's Goddard Space Flight Center. "The full moon is so immediate. It looks like a place you could go, you could stand on, you could visit." [See Amazing Images of the Full Moon]

She added that Carl Sagan once spoke about how the moon may have led to humans' desire to leave Earth and explore the universe, because other bodies, like the stars and planets, are so far away they aren't immediately visible.

"But the moon is so there; it's a part of our lives; it may have affected the way humans thought about the universe, our evolution as a culture," Thaller told LiveScience.

And this Sunday's full moon will be a close one. Since the moon takes an elliptical path around Earth, it can swing far away from us at one point on its orbit ??called apogee ? and super close during the lunar perigee.

Sunday's supermoon will reach its peak fullness at 7:32 a.m. EDT on Sunday (June 23), which is about 32 minutes after the moon reaches perigee; at this point, the moon will be about 221,300 miles (357,000 km) from Earth.

"The close timing of the moon's perigee and its full phase are what will bring about the biggest full moon of the year, a celestial event popularly defined by some as a 'supermoon,' said Joe Rao, as quoted by SPACE.com, a sister site to LiveScience.

At its closest and fullest, the supermoon will appear 12 percent larger than it will look during apogee on Jan. 16, 2014. The large ball in the sky has caused some to howl, it seems.

"A lot of the misconceptions are that this is somehow dangerous, that when the moon is a little bit closer, the gravity will cause earthquakes or tidal waves, or particularly high tides of any sort and that's just not true," Thaller said. "We've looked very hard to see if there were any correlations between where the moon is and natural disasters, and there just doesn't seem to be any relationship at all."

Thaller even mentioned that some thought that when they looked into a bowl of water under the light of the full moon they would see their future husband. "Unfortunately there really isn't any scientific basis for that," she added.

You can watch a free webcast of 2013 supermoon full moon on SPACE.com beginning on Sunday at 9 p.m. EDT (0100 June 24), courtesy of the skywatching website Slooh Space Camera.

Editor's note: If you snap an amazing photo of the Sunday Supermoon and you'd like to share it for a possible story or image gallery on SPACE.com, please send images and comments, including equipment used, to managing editor Tariq Malik at?spacephotos@space.com.

Follow Jeanna Bryner on Twitter?and Google+. Follow us @livescience, Facebook?& Google+. Original article on LiveScience.com.

Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/supermoon-humanitys-fascination-explained-153630397.html

rose parade bowl games rose bowl auld lang syne dick clark Happy new year fiscal cliff

Google celebrates the Manchester Baby and the birth of computer memory (video)

Google celebrates the Manchester Baby and the birth of computer storage video

As part of its efforts to promote the unsung heroes of computing history, Google is celebrating the Manchester Baby's 65th birthday. Despite the cutesy nickname, the Manchester Small Scale Experimental Machine was the first computer to use electronic memory rather than punchcards for programming, heralding the software revolution. The secret was in the Williams-Kilburn cathode-ray tube, which could store a (then) staggering 128 bytes worth of data. Of course, that's not much by modern standards, but given that the 5-meter machine weighed in at over a ton, we still think it could take your fancy laptop in a bar-room brawl. If you're curious to learn more and hear the immortal quips of Professor F.C. Williams, head on past the break for the video.

Filed under: ,

Comments

Source: Google

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/1VTI3vJgasg/

giuliana rancic elie wiesel temptations work hard play hard tim ferriss wmt human nature